US 10,092,541 B2
Methods for the treatment of diseases ameliorated by PDE4 inhibition using dosage titration of apremilast
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US 10,092,541 B2
Methods for the treatment of diseases ameliorated by PDE4 inhibition using dosage titration of apremilast
Tech Center:
1600 Biotechnology and Organic Chemistry
Examiner:
Bong-Sook Baek
Art Unit:
1621 Organic Chemistry
Agent:
Inventors:
Robert DAY
Assignee:
Priority:
08/15/14
Filed:
08/13/15
Granted:
10/09/18
Expiration:
08/15/34
Abstract
Methods of treating, managing or preventing diseases ameliorated by inhibiting PDE4 such as psoriasis, ankylosing spondylitis, Behcet's disease, rheumatoid arthritis, atopic dermatitis, Crohn's disease, and ulcerative colitis are disclosed. Specific methods encompass the administration of apremilast in specific dosage titration schedule, alone or in combination with a second active agent.
Cooperative Patent Classification (CPC)
A61A61K39/3955A61P19/02A61K

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