US 10,117,836 B2
TABLET FORMULATION FOR CGRP ACTIVE COMPOUNDSGeneral
US 10,117,836 B2
TABLET FORMULATION FOR CGRP ACTIVE COMPOUNDS
Tech Center:
1600 Biotechnology and Organic Chemistry
Examiner:
Leslie A. Royds Draper
Art Unit:
1629 Organic Chemistry
Inventors:
Mary Ann Johnson; Leonardo Resende Allain; W. Mark Eickhoff; Craig B. Ikeda; Chad D. Brown; Francis J. Flanagan; Rebecca Nofsinger; Melanie Marota; Lisa Lupton; Paresh B. Patel; Hanmi Xi; Wei Xu
Assignee:
Priority:
01/30/15
Filed:
07/28/16
Granted:
11/06/18
Expiration:
02/05/34
Abstract
The present invention is directed to compositions comprising an extrudate or solid solution of a compound, or a salt thereof, of Formula I (API): Formula I, wherein “Ra” is independently H or —F, in a water-soluble polymer matrix which further comprises a disintegration system allowing a tablet made therefrom to rapidly disintegrate in the environment in which the API is to be released.
Cooperative Patent Classification (CPC)
A61A61K31/4545A61P25/04A61K