US 10,457,666 B2
Stable crystal form of tipiracil hydrochloride and crystallization method for the sameGeneral
US 10,457,666 B2
Stable crystal form of tipiracil hydrochloride and crystallization method for the same
Tech Center:
1600 Biotechnology and Organic Chemistry
Examiner:
Dennis Heyer
Art Unit:
1628 Organic Chemistry
Inventors:
Hideki KAZUNO; Tomonobu MUTSUMI
Assignee:
Priority:
06/17/13
Filed:
05/02/18
Granted:
10/29/19
Expiration:
06/17/34
Abstract
Crystal Form I of 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrimidinedione hydrochloride exhibiting powder X-ray peaks at two or more angles selected from the group consisting of 11.6°, 17.2°, 17.8°, 23.3°, 27.1°, and 29.3° as a diffraction angle (2θ±0.2°).
Cooperative Patent Classification (CPC)
C07C07D403/06C07B2200/13C07DA61P35/00A61P