US 10,835,515 B2
CARBOXAMIDE DERIVATIVE AND ITS DIASTEREOMERS IN STABLE CRYSTALLINE FORMGeneral
US 10,835,515 B2
CARBOXAMIDE DERIVATIVE AND ITS DIASTEREOMERS IN STABLE CRYSTALLINE FORM
Tech Center:
1600 Biotechnology and Organic Chemistry
Examiner:
Kamal A Saeed
Art Unit:
1626 Organic Chemistry
Inventors:
Olli TÖRMÄKANGAS; Terhi HEIKKINEN
Assignee:
Priority:
01/28/16
Filed:
07/01/19
Granted:
11/17/20
Expiration:
01/28/36
Abstract
The present disclosure relates to solid crystalline forms of N—((S)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)-propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide (I) and the diastereomers thereof, and to methods for preparing such crystalline forms. Compound (I) and the diastereomers thereof are potent androgen receptor (AR) modulators useful as a medicament.
Cooperative Patent Classification (CPC)
A61A61K31/4155A61P35/00A61KC07D231/14C07D