US 6,369,085 B1
Form of S-omeprazoleGeneral
US 6,369,085 B1
Form of S-omeprazole
Tech Center:
1600 Biotechnology and Organic Chemistry
Examiner:
Jane Fan
Art Unit:
1625 Organic Chemistry
Agent:
Inventors:
HANNA COTTON; ANDERS KRONSTROM; ANDERS MATTSON; EVA MOLLER
Assignee:
Priority:
05/30/97
Filed:
05/05/98
Granted:
04/09/02
Expiration:
06/08/18
Abstract
The present invention relates to a novel form of the (−)-enantiomer of 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1H-benzimidazole, i.e. S-omeprazole. More specifically, it relates to a novel form of the magnesium salt of the S-enantiomer of omeprazole trihydrate. The present invention also relates to processes for preparing such a form of the magnesium salt of S-omeprazole and pharmaceutical compositions containing it. Furthermore, the present invention also relates to new intermediates used in the process.