US 7,411,070 B2
Form of S-omeprazoleGeneral
US 7,411,070 B2
Form of S-omeprazole
Tech Center:
1600 Biotechnology and Organic Chemistry
Examiner:
Charanjit S Aulakh
Art Unit:
1625 Organic Chemistry
Agent:
Inventors:
Hanna Cotton; Anders Kronstrom; Anders Mattson; Eva Moller
Assignee:
Priority:
05/30/97
Filed:
09/25/03
Granted:
08/12/08
Expiration:
09/14/20
Abstract
The present invention relates to a novel form of the (−)-enantiomer of 5-methoxy-2[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1H-benzimidazole, i.e. S-omeprazole. More specifically, it relates to a novel form of the magnesium salt of the S-enantiomer of omeprazole trihydrate. The present invention also relates to processes for preparing such a form of the magnesium salt of S-omeprazole and pharmaceutical compositions containing it. Furthermore, the present invention also relates to new intermediates used in the process.
Cooperative Patent Classification (CPC)
A61A61P31/04A61PC07D401/12C07D