US 7,563,922 B2
Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
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US 7,563,922 B2
Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
Tech Center:
1600 Biotechnology and Organic Chemistry
Examiner:
Venkataraman Balasubram
Art Unit:
1624 Organic Chemistry
Agent:
Laura Donnelly
Inventors:
Didier Philippe Robert Schils; Joannes Josephus Maria Willems; Bart Petrus Anna Medaer; Elisabeth Therese Pasquier; Paul Adriaan Jan Janssen; Jan Heeres; Ruben Gerardus Leenders; Jerome Emile Georges Guillemont
Assignee:
Janssen Pharmaceutica N.V.
Priority:
08/09/02
Filed:
04/23/07
Granted:
07/21/09
Expiration:
08/07/23
Abstract
Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]-amino]-2-pyrimidinyl]amino]benzonitrile of formula (I), a N-oxide, a pharmaceutically acceptable acid addition salt, a quaternary amine or a stereochemically isomeric form thereof are provided, said processes comprise:
Cooperative Patent Classification (CPC)
A61A61P31/18A61PC07D239/48C07C253/30C07D

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