US 7,888,101 B2
HOST CELLS COMPRISING ALPHA 1, 2 MANNOSIDASE AND CULTURE METHODS THEREOF
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US 7,888,101 B2
HOST CELLS COMPRISING ALPHA 1, 2 MANNOSIDASE AND CULTURE METHODS THEREOF
Tech Center:
1600 Biotechnology and Organic Chemistry
Examiner:
Christian L Fronda
Art Unit:
1652 Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzyme
Agent:
Michael G. Penn
Inventors:
Christopher K. Crowell
Assignee:
AMGEN INC.
Priority:
12/06/06
Filed:
12/06/06
Granted:
02/15/11
Expiration:
04/08/26
Abstract
Improved host cells and culture methods involving overexpression of MAN1C1 activity to improve protein production are provided.
Cooperative Patent Classification (CPC)
C07C07K14/505C07KC12N2501/999C12Y302/01024C12P21/005C12Q1/6809C12NG01N33/746G01N

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