US 8,357,795 B2
Hyaluronic acid-based gels including lidocaineGeneral
US 8,357,795 B2
Hyaluronic acid-based gels including lidocaine
Tech Center:
1600 Biotechnology and Organic Chemistry
Examiner:
Ali Soroush
Art Unit:
1617 Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
Agent:
Debra Condino, Stephen Donovan, Linda Fox
Inventors:
Pierre F. Lebreton
Assignee:
Priority:
08/04/08
Filed:
02/26/09
Granted:
01/22/13
Expiration:
04/08/30
Abstract
Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. In one aspect, hyaluronic acid-based compositions described herein include a therapeutically effective amount of at least one anesthetic agent, for example, lidocaine. The present hyaluronic acid-based compositions including lidocaine have an enhanced stability and cohesivity, relative to conventional compositions including lidocaine, for example when subjected to sterilization techniques or when stored for long periods of time. Methods and processes of preparing such hyaluronic acid-based compositions are also provided.
Cooperative Patent Classification (CPC)
A61A61Q19/001A61K2800/91A61L2300/602A61P29/00A61QC08L5/08C08L