US 9,018,243 B2
Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereofGeneral
US 9,018,243 B2
Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof
Tech Center:
1600 Biotechnology and Organic Chemistry
Examiner:
Rei-tsang Shiao
Art Unit:
1628 Organic Chemistry
Agent:
Inventors:
Peter H. SCHAFER; Chuansheng GE; George W. MULLER; Hon-Wah MAN; Jean XU
Assignee:
Priority:
03/20/02
Filed:
12/10/13
Granted:
04/28/15
Expiration:
03/20/22
Abstract
Solid forms comprising (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions comprising the solid forms, methods of making the solid forms and methods of their use are disclosed. The methods include methods of treating and/or preventing disorders ameliorated by the reduction of levels of TNF-α or the inhibition of PDE4.
Cooperative Patent Classification (CPC)
C07C07C317/28C07D209/48C07B2200/07C07CA61K31/4035A61P17/06A61K