US 9,388,134 B2 | COMPOUNDS CONTAINING S-N-VALERYL-N-{[2'-(1H-TETRAZOLE-5-YL)-BIPHENYL-4-YL]-METHYL}-VALINE AND (2R,4S)-5-BIPHENYL-4-YL-4-(3-CARBOXY-PROPIONYLAMINO)-2-METHYL-PENTANOIC ACID ETHYL ESTER MOIETIES AND CATIONS

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US 9,388,134 B2

COMPOUNDS CONTAINING S-N-VALERYL-N-{[2'-(1H-TETRAZOLE-5-YL)-BIPHENYL-4-YL]-METHYL}-VALINE AND (2R,4S)-5-BIPHENYL-4-YL-4-(3-CARBOXY-PROPIONYLAMINO)-2-METHYL-PENTANOIC ACID ETHYL ESTER MOIETIES AND CATIONS

Tech Center:

1600 Biotechnology and Organic Chemistry

Examiner:

Timothy Thomas

Art Unit:

1628 Organic Chemistry

Agent:

David R. Kurlandsky

Inventors:

Sven Erik Godtfredsen; Mahavir Prashad; Bin Hu; Lili Feng; Paul Allen Sutton; Michael J. Girgis; Yugang Liu; Piotr Henryk Karpinski; Thomas J. Blacklock

Assignee:

NOVARTIS PHARMACEUTICALS CORPORATION

Priority:

06/23/14

Filed:

06/23/14

Granted:

07/12/16

Expiration:

11/09/25

Abstract

A method for treatment of a cardiovascular or renal condition or disease with a specific combination, linked pro-drug or a compound of an angiotensin receptor antagonist and a NEPi.

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