US 9,421,265 B2
AQUEOUS PHARMACEUTICAL COMPOSITIONS CONTAINING BORATE-POLYOL COMPLEXES
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US 9,421,265 B2
AQUEOUS PHARMACEUTICAL COMPOSITIONS CONTAINING BORATE-POLYOL COMPLEXES
Tech Center:
1600 Biotechnology and Organic Chemistry
Examiner:
Theodore R West
Art Unit:
1628 Organic Chemistry
Agent:
Scott A. Chapple
Inventors:
Bhagwati P. Kabra
Assignee:
ALCON INC.
Priority:
06/17/10
Filed:
04/20/15
Granted:
08/23/16
Expiration:
06/19/29
Abstract
The present invention is directed to the provision of multi-dose, ophthalmic compositions. The compositions possess sufficient antimicrobial activity to satisfy USP preservative efficacy requirements, as well as similar preservative standards (e.g., EP and JP). The compositions include at two different polyols in conjunction with borate and a low concentration of benzalkonium chloride.
Cooperative Patent Classification (CPC)
A61A61K2300/00A61P27/02A61K

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