US 9,446,912 B2
Multilayer hydrodynamic sheath flow structureGeneral
US 9,446,912 B2
Multilayer hydrodynamic sheath flow structure
Tech Center:
3600 Transportation, Construction, Electronic Commerce, Agriculture, National Security and License and Review
Examiner:
Joseph Dillon, Jr.
Art Unit:
3651 Material and Article Handling
Agent:
Inventors:
Manish Deshpande; John R. Gilbert; Bernard Bunner
Assignee:
Priority:
10/30/03
Filed:
08/16/13
Granted:
09/20/16
Expiration:
04/09/24
Abstract
A microfabricated sheath flow structure for producing a sheath flow includes a primary sheath flow channel for conveying a sheath fluid, a sample inlet for injecting a sample into the sheath fluid in the primary sheath flow channel, a primary focusing region for focusing the sample within the sheath fluid and a secondary focusing region for providing additional focusing of the sample within the sheath fluid. The secondary focusing region may be formed by a flow channel intersecting the primary sheath flow channel to inject additional sheath fluid into the primary sheath flow channel from a selected direction. A sheath flow system may comprise a plurality of sheath flow structures operating in parallel on a microfluidic chip.
Cooperative Patent Classification (CPC)
G01G01N15/1409G01NB01L2300/0816B01F33/3011B01J2219/00833B01LB65G51/00B65GB07C5/34B07C