US 9,522,188 B2
Abuse resistant transmucosal drug delivery deviceGeneral
US 9,522,188 B2
Abuse resistant transmucosal drug delivery device
Tech Center:
1600 Biotechnology and Organic Chemistry
Examiner:
Michael G Hartley
Art Unit:
1618 Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
Agent:
Inventors:
Andrew Finn; Niraj Vasisht
Priority:
12/13/05
Filed:
12/13/06
Granted:
12/20/16
Expiration:
04/24/34
Abstract
The present invention relates to a solid pharmaceutical dosage form for abusable drug delivery with reduced illicit abuse potential. The dosage form is presented as a bioerodable transmucosal delivery device that includes an abusable drug and an antagonist to the abusable drug associated with an abuse-resistant matrix. The devices of the invention may be in the form of a layered film or a tablet. Upon application in a non-abusive manner, the device adheres to the mucosal surface, providing transmucosal drug delivery of the drug with minimal absorption of the antagonist into systemic circulation.
Cooperative Patent Classification (CPC)
A61A61K2300/00A61P25/30A61K