US 9,738,929 B2
Nucleic acid sequence analysisGeneral
US 9,738,929 B2
Nucleic acid sequence analysis
Tech Center:
1600 Biotechnology and Organic Chemistry
Examiner:
Cynthia B Wilder
Art Unit:
1637 Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
Inventors:
Stephen Turner; Jon Sorenson; Kenneth Mark Maxham; John Eid; Cheryl Heiner; Kevin Travers
Priority:
03/28/08
Filed:
12/19/16
Granted:
08/22/17
Expiration:
09/24/28
Abstract
Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.
Cooperative Patent Classification (CPC)
C12C12Q2537/149C12N9/1252C12QG16B30/00G16BG01N2021/6439G01N