US 9,884,908 B2
Methods for treating headache using antagonist antibodies directed against calcitonin gene-related peptideGeneral
US 9,884,908 B2
Methods for treating headache using antagonist antibodies directed against calcitonin gene-related peptide
Tech Center:
1600 Biotechnology and Organic Chemistry
Examiner:
Christine J Saoud
Art Unit:
1647 Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
Agent:
Inventors:
Joerg Zeller; Kristian T. Poulsen; Yasmina Noubia Abdiche; Jaume Pons; Sierra Jones Collier; Arnon Rosenthal
Priority:
11/14/05
Filed:
05/05/17
Granted:
02/06/18
Expiration:
11/14/25
Abstract
The invention features methods for preventing or treating CGRP associated disorders such as vasomotor symptoms, including headaches (e.g., migraine, cluster headache, and tension headache) and hot flushes, by administering an anti-CGRP antagonist antibody. Antagonist antibody G1 and antibodies derived from G1 directed to CGRP are also described.
Cooperative Patent Classification (CPC)
A61A61K2039/505A61P29/00A61KC07K2317/567C07K